Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets.

The experiment was conducted to study the effects of sodium butyrate (SB) on growth, haematological and immunological characteristics in weanling pigs. A total of 100 male piglets (Duroc×Landrace×Yorkshire) with a body weight of 8.0 ± 0.2 kg weaned at the age of 28 days were randomly assigned to two treatments with five replicates and 10 pigs per replicate. Piglets received a basal diet (control group) or diets supplemented with 1000 mg/kg SB. The feeding trial lasted for 21 days. The results showed that dietary SB significantly decreased (p < 0.05) diarrhoea incidence of weaned piglets, but did not affect (p > 0.05) the average daily feed intake (ADFI), average daily gain (ADG) and feed to gain (F/G). Furthermore, piglets fed dietary SB had higher (p < 0.05) serum concentrations of glucose and triglycerides and lower (p < 0.05) serum concentrations of urea nitrogen, cortisol, D-lactic acid and diamine oxidase when compared with the control group. However, dietary SB did not affect concentrations of serum albumin, total protein, insulin and glucagon (p > 0.05). There were no significant (p > 0.05) treatment effects on serum IgA and IgM, whereas serum IgG concentration and IgA+ cell count in jejunum from pigs fed SB were significantly higher (p < 0.05) than in those given the basal diet. In conclusion, the present study indicated that dietary SB significantly decreased diarrhoea incidence of weaned piglets and increased the efficiency of nitrogen utilization. Also, dietary SB could regulate and enhance the immune function of piglets by increasing the serum IgG concentration and IgA+ cell count in jejunum. Our results suggest that SB may reduce some of the adverse effects of weaning stress and play an important role in maintaining the integrity of intestinal mucosa.

Effects of zinc glycine chelate on growth, hematological, and immunological characteristics in broilers.

Three hundred sixty healthy Ross x Ross 1-day-old broilers were used to study the effects of zinc glycine chelate (Zn-Gly) on growth performance, hematological, and immunological characteristics. All broilers were randomly assigned into six treatments. Diets were as follows: (1) control (containing 29.3 mg Zn kg(-1) basic diet [0-3 weeks] and 27.8 mg Zn kg(-1) [4-6 weeks]); (2) basic diet plus 30 mg Zn kg(-1) from Zn-Gly; (3) basic diet plus 60 mg Zn kg(-1) from Zn-Gly; (4) basic diet plus 90 mg Zn kg(-1) from Zn-Gly; (5) basic diet plus 120 mg Zn kg(-1) from Zn-Gly; (6) positive control, basic diet plus 120 mg Zn kg(-1) from zinc sulfate (ZnSO(4)). After the 21- and 42-day feeding trials, the results showed that both of Zn-Gly and ZnSO(4) could improve the growth performance of broilers, with the greatest average daily feed intake observed in the broilers fed 90 mg Zn kg(-1) from Zn-Gly, but the greatest average daily gain observed with 120 mg Zn kg(-1) from Zn-Gly (0-3 weeks) and 90 mg Zn kg(-1) from Zn-Gly (4-6 weeks). Adding additional Zn-Gly improved the levels of immunoglobulins (IgA, IgM, and IgG) and the contents of total protein and Ca in serum and increased the immune organs index especially with 90 mg Zn kg(-1) as Zn-Gly. However, there were no significant differences in responses to complements (C3 and C4) and albumin in serum among the treatments.

Thermal symmetry of skin temperature: normative data of normal subjects in Taiwan.

BACKGROUND: The aims of this study were (a) to establish normative data of thermal symmetry (left vs. right) in normal subjects; (b) to compare the skin temperature in various regions between young and old people in Taiwan and between male and female. METHODS: The skin surface of 57 healthy volunteers (aged 24 to 80 yr) was divided into 25 areas and measured by an infrared thermography (Avionics TVS-2000, Japan). The average temperatures of these 25 regions were compared: (a) left vs. right side, (b) young (< or = 60 yr, n = 37) vs. old (> 60 yr, n = 20), and (c) male vs. female. Student's t-test was used to assess means between both groups. RESULTS: The neck carried the highest skin temperature (31.9 degrees C +/- 0.6; mean +/- SD) of the body in comparison with the toes that had the lowest one (27.5 degrees C +/- 2.0). The side-to-side temperature differences were subtle, which did not exceed 0.5 degrees C. The average skin temperature of elderly was slightly lower than that of young subjects in 11 out of 25 areas (p < 0.05), especially the distal parts of extremities. Elderly female had lower skin temperature in various truncal areas as compared with their counterpart. However, the skin temperature was higher in the distal extremity (p < 0.05). CONCLUSIONS: The thermoregulatory system is substantially symmetrical. The result of this study offered valuable normative database on skin thermal symmetry in normal population of Taiwan, and may be useful as a diagnostic aid in patients with various states of disorders associated with autonomic dysfunctions.